Changes in the Activity of Enzymes Primarily Not Synthesized in the Liver Following the Infection Rabbits with Intestinal Coccidia

Abstract

Two groups of rabbits, 10 animals each, were experimentally infected with varying doses of sporulated intestinal coccidia oocysts. The infectious material was composed of several rabbit intestinal coccidia oocyst species: Eimeria flavescens (7%), E. matsubayashi (9%), E. magna (12%), E. neoleporis (19%), E. perforans (21%) and E. media (32%). The third group of rabbits served as a control. Following the experimental infection, a subclinical form of the disease was induced in the rabbits while only 3 animals developed a full-blown disease with diarrhea. Shortly before and then on day 4, 7 and 10 after the infection, levels of the following blood enzymes were determined: creatin kinase, gamma glutamil transferase, amylase and alkaline phosphatase. A decrease in the activity of creatin kinase and a rise in the activity of amylase and alkaline phosphatase were registered. The activity of gamma glutamil transferase was within normal limits.