Article ID: 2024-0044
Objectives: This study aimed to compare the quality of scarring of DERMABOND PRINEO (Ethicon, Inc., Somerville, NJ, USA) ® by conducting a half-side test on the same wound to determine its superiority. If the utility of DERMABOND PRINEO® is established, its use can be expanded for more cases and higher quality medical care can be provided.
Methods: Patients who underwent two-stage breast reconstruction were included. The first surgery was half closed with DERMABOND PRINEO® and nylon threads, and the time was measured. At the second surgery, all scars were removed, and a histopathological examination was done. Scars were evaluated with the Vancouver Scar Scale (VSS) and visual analogue scale (VAS), and statistical analysis was performed.
Results: Time to closure was significantly shorter in the DERMABOND PRINEO® group. Postoperative VSS scores for pliability were significantly lower in the suture group, and the total VSS score was significantly lower in the suture group from 3 to 6 months postoperatively. Patients rated postoperative wound pain, itching, appearance, and satisfaction with the VAS, but no significant differences were observed between the two groups. The scars were compared with hematoxylin-eosin staining and Elastica van Gieson staining. Differences were seen in the increase of elastic fibers in the dermal reticular layer, a characteristic difference between the two groups.
Conclusions: The use of DERMABOND PRINEO® leads to a reduction in operative time and impacts the maturity of the scar. It is expected that the indications for DERMABOND PRINEO® can be further expanded in the future.
