Abstract
Immune responses to several antigens, such as sheep red blood cell (SRBC), bovine serum albumin (BSA), lipopolysaccharides (LPS) of E. coli and S. minnesota, dog serum albumin (DSA) and bovine red blood cell (BRBC) were examined using the lines of chickens selected for the high (HR) and low (LR) immune responses to rabbit serum albumin (RSA). The birds at the second, third and fifth generations of selection were used for the immunization.
The HR line showed significantly higher immune responses to SRBC, both LPS and DSA than did the LR line. On the other hand, the line differences of the immune responses to BSA and BRBC were not significant. Since the immune response to T-cell independent antigens, LPS in this experiment, was similar to that to T-cell dependent antigens, SRBC, it was suggetsed that the immune responses to both types of antigens might be under controll of the same genes.
