Study on Tumor inhibition of Dichloromethane Extract from Blumea balsamifera D. C. in Lewis Lung Cancer Mice

Huoqiang Huang; Huichang Jiang; Yachen Zhang; Jie Li

doi:10.1254/jpssuppl.WCP2018.0_PO1-9-8

WCP2018 (The 18th World Congress of Basic and Clinical Pharmacology)

セッションID: WCP2018_PO1-9-8

DOI https://doi.org/10.1254/jpssuppl.WCP2018.0_PO1-9-8

会議情報

主催: The Japanese Pharmacological Society, The Japanese Society of Clinical Pharmacology

会議名: WCP2018 (18th World Congress of Basic and Clinical Pharmacology)

開催地: Kyoto

開催日: 2018/07/01 - 2018/07/06

Poster session

Study on Tumor inhibition of Dichloromethane Extract from Blumea balsamifera D. C. in Lewis Lung Cancer Mice

Huoqiang Huang, Huichang Jiang, Yachen Zhang, Jie Li

著者情報

キーワード: Blumea balslmifera D.C., Lewis lung cancer

会議録・要旨集オープンアクセス

詳細

抄録

Blumea baslamefera DC. is one of the widely used anti¯lung cancer herbs in Yi nationality in China. On the preliminary studies, the anti¯lung cancer effect of dichloromethane extract from Blumea balsamifera DC. on Lewis lung cancer mice was studied. Lewis lung canceer mice model was established in C57BL/6J mouse. Pathological changes in tumor tissues were observed by H.E. staining. The expressions of VEGF and TNFα were detected by using immunohistochemistry method. Results whowed that the dichloromethane extract from Blumea balsamifera DC. could significantly exhibited the grouth of Lewis lung cancer in mice, comparing to the model group (P<0.05 or P<0.01). The average optical densities of VEGF and TNFα were significantly increased in each treatment group versus model group (P<0.05).

責任著者(Corresponding author)

会議情報

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