ノート
Rotating Dialysis Cell法による市販イブプロフェン製剤の溶出挙動
1997 年 57 巻 4 号 p. 204-208
詳細
1997 年 57 巻 4 号 p. 204-208
Recently, nonprescription switch OTC drugs have attracted a great deal of attention, and many such drugs are being developed. Among these drugs, ibuprofen is contained in many brands and various dosage forms on the market. Dissolution tests were performed for ibuprofen preparations both by the paddle (PD) method described in the Japanese Pharmacopoeia (JP) and by the rotating dialysis cell (RDC) method. Dissolution behavior tested by the RDC method more accurately represented pharmaceutical characteristics of these preparations than that when tested by the PD method.
