Effect of Salicylic Acid Ointment by Occlusive Dressing Technique for Human Keratinocyte

Abstract

We studied the effects of salicylic acid ointment by using the occlusive dressing technique (ODT) on keratinized human heel skin. The amount of sweat induced by ODT increased in comparison with that by a simple application method (control). Moreover, we observed that the morphological changes in the softening of keratinized heel skin by ODT were faster than those by the control method. The present results clearly indicated that ODT of salicylic acid ointment induced the softening of keratinized heel skin.