There have been several reports about compatibility in the mixing of eye drops. A large part of the reports examined the mixing of two kinds of eye drops, and then observed only visual changes in appearance after mixing. To assess the compatibility, we attempted to develop an examination by mixing artificial tears with eye drops. In addition, we measured the number of minute particles and the contents of drugs. We selected 14 combinations that were used in our hospital for outpatients. By adding the artificial tears, the number of minute particles and the contents of drugs were improved. As a result, this method with artificial tears was helpful to evaluate compatibility in mixing eye drops.
