1995 Volume 41 Issue 3 Pages 209-212
To evaluate the correlation between luteolysis and T lymphocytes (T-cells) found in the corpus luteum (CL), peripheral blood lymphocyte (PBL) blastogenesis to mitogens tested for the presense of luteolytic factor(s) in the supernatant culture medium of luteal tissues from various stages of pseudopregnancy (PSP). PBL blastogenesis was measured by 3H-thymidine uptake. The culture medium of luteal tissue from Day 15 PSP caused a significantly high 3H-thymidine uptake in the Con A stimulation group of the PBL blastogenesis test. The present finding suggests the presence of some factors which activate in the regressive CL.