Abstract
The mouse myogenin gene carrying the LacZ gene coding for β-galactosidase was microinjected into fertilized eggs of dystrophic (dy/dy) mice. Concentrations of the LacZ gene varied between the fast and slow regions of skeletal muscle. The slow or gastrocnemius muscle region, exhibited unusually high levels of the LacZ gene compared to the levels found in the fast muscle region which is also known as the extensor digitorum longus muscle (EDL). In addition, morphological studies indicated that a maturational defect was present in the dystrophic dy/dy EDL muscle.
