Abstract
The ovulatory response was examined in the adult Japanese cat using various kinds of gonadotropins.
Results obtained are summarized as follows.
1. In diestrous cats, estrus was induced 3 days after the combined treatment of 100 IU PMS followed by 50 IU two days later.
2. In PMS-induced estrous animals, ovulation occurred in all of the animals 36 hrs after the single sc injection of gonadotropin (porcine FSH, ovine GTH or HCG), but none ovulated 27 hrs after the treatment.
3. For induction of ovulation in 50% of the animals, the amount of porcine FSH, equine LH, unfractionated ovine GTH, HCG or synthetic LH-RH was estimated as 0.075 AU, 1200 μg, 0.0234 RU, 6 IU or 4.8 μg, respectively.
4. The amounts of various kinds of gonadotropins estimated for induction of ovulation in 50% of diestrous mice were defined as one unit, and the amounts of gonadotropin were compared for their effectiveness in inducing 50% ovulation in various kinds of animals: the amount of FSH in rats, rabbits or cats was estimated as 6, 51, or 7, respectively; that of LH as 12, 96 or 48; that of ovine GTH as 7, 254 or 4; that of HCG as 16, 131 or 8; that of LH-RH as 16, 32 or 128.
These data suggested that LH and LH-RH are less effective for induction of ovulation in cats than FSH, ovine GTH or HCG.
