Abstract
Adenylate cyclase (AC) activity in mouse oocytes immediately after ovulation was electron histochemically detected by the method of Wagner et al., and compared among the 3 age groups of 30-day-old, 60- to 90-day-old and 180- to 210-day-old animals. AC activity was detected as lead granules, high in electron density on the cytoplasmic membrane. The activity was found in all the oocytes, but the intensity was highest in 30-day-old mice and lowest in 180- to 210-day-old ones with statistically significant differences.
