2026 Volume 21 Issue 2 Pages 225-230
Objective: Remnant cystic duct cancer is a rare disease, with only a few reported cases. We report a case of remnant cystic duct cancer that gradually increased in size.
Patient: A 78-year-old woman with a history of cholecystectomy presented with a gradually enlarging mass at the porta hepatis after laparoscopic liver resection for hepatocellular carcinoma.
Results: Diagnostic imaging, including computed tomography and magnetic resonance imaging, showed a mass at the porta hepatis near a surgical staple, which gradually increased in size over two years. Endoscopic ultrasonography revealed a mass in the cystic duct enhanced with perfluorobutane. Resection of the extrahepatic bile duct with choledochojejunostomy was performed. Histopathological examination revealed a well-differentiated adenocarcinoma at the site where the cystic duct protrudes into the common bile duct opening. The patient remains alive two years after surgery without recurrence or metastasis.
Conclusion: Remnant cystic duct cancer is extremely rare and often presents at an advanced stage. This case demonstrated a slow, asymptomatic progression, offering new insight into its natural history.