Journal of Rural Medicine
Online ISSN : 1880-4888
Print ISSN : 1880-487X
ISSN-L : 1880-487X
Case report
Remnant cystic duct cancer with gradual enlargement over two years of follow-up: a case report and literature review
Takashi KondoHiroyuki ArigaNaoki IsoKenta OkadaKohei OnoJunya Kashimura
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JOURNAL OPEN ACCESS

2026 Volume 21 Issue 2 Pages 225-230

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Abstract

Objective: Remnant cystic duct cancer is a rare disease, with only a few reported cases. We report a case of remnant cystic duct cancer that gradually increased in size.

Patient: A 78-year-old woman with a history of cholecystectomy presented with a gradually enlarging mass at the porta hepatis after laparoscopic liver resection for hepatocellular carcinoma.

Results: Diagnostic imaging, including computed tomography and magnetic resonance imaging, showed a mass at the porta hepatis near a surgical staple, which gradually increased in size over two years. Endoscopic ultrasonography revealed a mass in the cystic duct enhanced with perfluorobutane. Resection of the extrahepatic bile duct with choledochojejunostomy was performed. Histopathological examination revealed a well-differentiated adenocarcinoma at the site where the cystic duct protrudes into the common bile duct opening. The patient remains alive two years after surgery without recurrence or metastasis.

Conclusion: Remnant cystic duct cancer is extremely rare and often presents at an advanced stage. This case demonstrated a slow, asymptomatic progression, offering new insight into its natural history.

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© 2026 by THE JAPANESE ASSOCIATION OF RURAL MEDICINE

この記事はクリエイティブ・コモンズ [表示 - 非営利 - 改変禁止 4.0 国際]ライセンスの下に提供されています。
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
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