Protective Effects of Vitamin Glycosides on γ-radiation and H2O2-Induced Decomposition of Thymine in Aqueous Solutions

Oleg SHADYRO; Petr LAGUTIN; Irina EDIMECHEVA; Svyatoslav BRINKEVICH; Tsutomu KAGIYA

doi:10.1269/jrr.08004

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Protective Effects of Vitamin Glycosides on γ-radiation and H₂O₂-Induced Decomposition of Thymine in Aqueous Solutions

Oleg SHADYRO, Petr LAGUTIN, Irina EDIMECHEVA, Svyatoslav BRINKEVICH, Tsutomu KAGIYA

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Keywords: Thymine, Radiolysis, Radical, Vitamine Glycosides

JOURNAL FREE ACCESS

2008 Volume 49 Issue 4 Pages 431-435

DOI https://doi.org/10.1269/jrr.08004

View "Advance Publication" version (April 22, 2008).

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Abstract

Effects of ascorbic acid (AA), ascorbic acid glycoside (AAG) and α-tocopherol monoglycoside (TMG) on radiation - and H₂O₂-induced decomposition of thymine in aqueous solutions were investigated. Of the three compounds studied, AAG was found to possess the most marked protector properties. An explanation of this phenomenon has been given in terms of differences in molecular structures of AA and AAG, as well as properties of radical adducts formed during their interaction with OH radicals.

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