Abstract
The in vivo effects of malonate, succinate and glucose on 137Cs uptake by muscles of pigeon have been studied. At 15 pg malonate/g body the radionuclide uptake in red muscle, white muscle, cardiac muscle and smooth muscle was found to be reduced by 27%, 14%, 23% and 27% respectively in comparison to the controls. The inhibition of radiocesium uptake has been even more pronounced at 25μg malonate/g body with as much as 68 % reduction of uptake in red muscle. Succinate and glucose enhanced the uptake of 137Cs in varying degrees in all the muscles. Moreover, both succinate and glucose could overcome the inhibitory effect of malonate in all the tissues except smooth muscle.
