Journal of Radiation Research
Online ISSN : 1349-9157
Print ISSN : 0449-3060
Localization of Free Radicals on Irradiated Deoxyribonucleohistone
桑原 幹典林 正信吉井 義一
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1973 年 14 巻 2 号 p. 198-203

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Deoxyribonucleohistone (DNH) from calf-thymus was studied by E. S. R. spectroscopy following gamma-irradiation. Free radicals formed in gamma-irradiated deoxyribonucleohistone were mainly localized in DNA moeity. The G-value for radical production in DNH was 1.6, while the G-values in DNA and histone were 1.1 and 2.1, respectively. Thus the spectrum obtained in deoxyribonucleohistone could be explained as a consequence of an electron transfer from histone to DNA. This observation was also confirmed from E. S. R. spectrum of the reconstituted deoxyribonucleohistone.
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