Journal of Radiation Research
Online ISSN : 1349-9157
Print ISSN : 0449-3060
Change in Radiosensitivity on the Development of Sea Urchin Eggs during the Early Cleavage Stage II. Protection against X-ray Irradiation by Cysteamine
中村 泉
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ジャーナル フリー

1975 年 16 巻 4 号 p. 203-210

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The effect of cysteamine on the fluctuation of X-ray sensitivity during early cleavage stage of sea urchin eggs expressed by pluteus formation rate was examined. Sea urchin eggs were very resistant to radiation immediately after insemination or after S phase of the cleavage. When irradiation was given just prior to S phase or in the phase of cytokinesis, the eggs were very sensitive. In these sensitive stages, existence of cysteamine during X-irradiation apparently protected eggs against radiation effect. Dose modifying factor increased linearly from 1.8 to 3.4 with increasing dose of cysteamine (25 mM-75 mM) added.
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