抄録
4NQO-DNA mixture solution was irradiated with 60Co gamma-rays. Binding yield of 4NQO to DNA was compared to that of cysteine to DNA after fractionation by gel filtration. Their binding yields increased with increase in radiation dose. The dose vs binding yield curves of cysteine to single stranded DNA, cysteine to double stranded DNA, and 4NQO to double stranded DNA showed first order kinetics, but that of 4NQO to single stranded DNA was found to be different from the others i.e. it showed that the reaction was a second power function of radiation dose.
