Journal of Radiation Research
Online ISSN : 1349-9157
Print ISSN : 0449-3060
Response of Mice Liver to Continuous β-Irradiation from Tritiated Water
A. L. BHATIAM. L. GUPTAR. P. SINGH
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1978 Volume 19 Issue 3 Pages 197-204

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Abstract
The low-level toxicity of the tritium has been studied on the adult mice liver. A group of adult mice was irradiated continuously at the radioactivity of 1.25 μCi/ml of drinking water up to 30 days and the liver was studied on 1, 5, 7, 15 and 30 days after initiation of treatment. In early intervals, a gradual increase in the degree of damage in the form of histopathological lesions like cytoplasmic vacuolation and degranulation, pycnosis, hemorrhage and lymphocytic infiltration etc. was noticed which reaches to maximum on day 7, after which it was found a bit repaired on the following interval (15 days) and on 30th day exhibited almost a near-normal hepatic architecture with a few histopathological lesions viz. edema and leukocytic infiltration.
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