Overview of Immunological Studies on A-bomb Survivors A Review of Forty-Five Years Study of Hiroshima and Nagasaki Atomic Bomb Survivors II. BIOLOGICAL EFFECTS

MITOSHI AKIYAMA; YOICHIRO KUSUNOKI; SEISHI KYOIZUMI

doi:10.1269/jrr.32.SUPPLEMENT_301

Overview of Immunological Studies on A-bomb Survivors

A Review of Forty-Five Years Study of Hiroshima and Nagasaki Atomic Bomb Survivors II. BIOLOGICAL EFFECTS

MITOSHI AKIYAMA, YOICHIRO KUSUNOKI, SEISHI KYOIZUMI

著者情報

キーワード: Immune responses PHA, MLR, Lymphocyte subsets

ジャーナルフリー

1991 年 32 巻 SUPPLEMENT 号 p. 301-309

DOI https://doi.org/10.1269/jrr.32.SUPPLEMENT_301

詳細

抄録

Among the peripheral blood lymphocytes, T-cells and B-cells significantly decreased in number with age. Radiation exposure resulted in further significant decrease of T-cell count (but not B cells) in the elderly. T-cell response to PHA and allo-antigens also decreased with dose in the elderly group. In contrast, NK cell number and function increased with age while a significant dose effect was not observed.

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