抄録
The charged-particle microbeam, which allows irradiation of cells individually with micron precision and with precise number of charge particles, provides a unique opportunity to address the effect of low levels of ionizing radiation. Heavy ions are particularly effective and different from low-LET radiation for charged particle therapy. Then the heavy-ion microbeam program for irradiation of cells is started. The ion beam was accelerated by an 8 MV tandem Van de Graaff accelerator. Using a pair of apertures with 5 &mum hole and 6 &mum hole as the final collimator, carbon microbeam of 42 MeV was extracted to the atmosphere with low background particles. The range of the beam is about 80 &mum in water and long enough. An 10 &mum transmission scintillator and a photomultiplier tube detected the extracted particles with good efficiency. New vertical beam line is installed in order to irradiate the biological targets supported horizontally.
