抄録
Evidence is accumulating that irradiated cells produce some signals which interact with non-exposed cells in the same population. Understanding this Bystander effect from ionizing radiation is important for understanding radiation biology. Since 1990s, particle microbeam facilities have been available for biological study in Columbia University and Gray Cancer Institute. As it is possible to irradiate a specific number of cells on a cell population and a specific area of a cell in these facilities, it has been a powerful tool for bystander study. In this presentation, I would like to talk about some phenomena and mechanisms regarding bystander responses that have been elucidated by using these microbeam facilities.
