Host: The Japan Radiation Research Society
Nuclear reaction, 10B (n,4He) 7Li is used for Boron Neutron Capture Therapy (BNCT). As a result of this, very high LET radiations of 4He and 7Li are emerged. LET values of these are similar, and about 160 keV/μm. 10B-compound (BPA and BSH) is injected to a patient's body through a vein. When the compound as these is concentrated in a tumor higher than in normal tissues, the tumor is selectively destroyed. The faculty of BNCT as a modality of cancer therapy has been made clear by co-operative endeavor of Kyoto University Research Reactor Institute (KURRI)-BNCT community. At the end of 2001, first trial in the world of BNCT to Head & Neck cancer (recurrent mucoepidermoid carcinoma) was done by the use of epithermal neutrons from the Kyoto university reactor (KUR). Clinical result of this treatment was very excellent, and the malignant tumor of this case is controlled for four years. KUR-BNCT group stimulated by this hoped to statistically explain on the basis of the abundant case data that BNCT is one of the best modality to control a cancer. Moreover, we hope to develop an accelerator- based BNCT to spread this modality for more and more patients.
In this report, I will talk about a summary of BNCT managed KUR-BNCT group, the existing state of an accelerator dedicated for BNCT and so on.
