Abstract
We have reported that the radon and thermal therapy alleviated life style diseases, such as osteoarthritis. We examined the temporal changes in atrial natriuretic polypeptide (hANP) and arginine vasopressin (AVP) in human blood to elucidate the mechanism of alleviation of hypertension by the radon or the thermal treatment. Every 2 days, nasal inhalation of radon and mist using the radon and mist generator (the joint development with OZ PLAN (Okayama)) was performed for 30 min under a condition of high humidity (radon group;1496 Bq/m3, 30°C, thermal group; 33Bq/m3, 42°C). Blood samples were collected after each treatment on weeks 2 and 4 after first treatment. Results show that, in the radon group and in the thermal group, the maximum blood pressures and the minimum blood pressure in the hypertensive group (on weeks 2 and 4 after the first treatment) were significantly decreased compared with the control (before the first treatment). On weeks 4, in the hypertensive group and in the normal group, the hANP level in the radon group is larger than that in the thermal group. On weeks 4, in the hypertensive group, the AVP level in the radon group decreases to the normal level. These findings suggest that the radon treatment or the thermal treatment decreases blood pressure similar to normal level. Moreover the decrease of blood pressures is related to the increase of the hANP level and the decrease of the AVP level as the mechanism of alleviation of hypertension by the radon treatment. Moreover we will refer to the result of the synergistic radon and thermal effects.