Abstract
Accumulating evidences indicate that the biological effects of low dose radiation are different from those of high dose radiation. To evaluate the biological effects of low dose radiation certainly, experimental or epidemiological results in low dose region are really important. However, there are many issues, such as the population, the dispersion in the effect among individuals, the difference in experimental procedure, dosimetry, and so on. In addition, non-targeted effects such as bystander response have been reported without dose dependence and their biological mechanism has not yet fully elucidated. On the other hand, the study using animal model has found that the animals show radiation resistance in consequence of the defense response activated by low dose radiation. At this symposium, we would like to introduce recent studies of the biological effects of low dose radiation from various viewpoints and to discuss dose response, dose region to be evaluated and their biological meanings.