Laser Desorption Ionization Imaging Mass Spectrometry for Surface Analysis

Abstract

Developments of matrix-assisted laser desorption/ionization (MALDI) have been expanded the application field of organic mass spectrometry. Recently, imaging mass spectrometry (IMS), which enables to visualize localization of specific organic compounds, is improved in biological field. It is also expected to apply in industrial field as surface analytical tools; however, the application is still limited. In the industrial field, the probing depth from the sample surface is important as well as lateral resolution. In this paper, we have studied laser desorption/ionization (LDI-IMS) for using two-layered sample made by organic light emitting diode materials. We also studied difference between solvent-base matrix-assisted LDI-IMS (MALDI-IMS) and solvent-free surface-assisted LDI-IMS (SALDI-IMS) using silver deposition method using two-layered sample made by Irganox 1010 and Irganox 3114.