大気圧低温プラズマ及び臍帯血による低酸素脳症治療を目的とした低酸素脳症モデルラットに対する投与条件と効果の検討

抄録

　Although the mechanism of action remains unclear, new biomedical applications of plasma have been found. In addition, umbilical cord blood is clinically applied by hematopoietic stem cell transplantation. It was confirmed that mesenchymal stem cells capable of differentiating into brain and bone tissues exist in umbilical cord blood. It is expected that umbilical cord blood will be applied to the field of regenerative medicine from the existence of mesenchymal stem cells. On the other hand, hypoxic-ischemic encephalopathy (HIE) is a condition in which the brain does not receive enough oxygen. HIE is a fatal condition for brain falls into acid deficient state. Cause of HIE is various, for example, respiratory failure and circulatory failure, neonatal asphyxia. We want to conduct an experiment on the functional recovery of the HIE by atmospheric pressure plasma inhalation. We guessed the effect of the plasma and umbilical cord blood to the HIE model rats, was studied administration method.