Apply PCA to Extract the Relations between Metastasis and Gene Mutations on Pancreatic Cancer

Abstract

Pancreatic cancer is one of the most difficult cancers to recovery. The survival time rate of 5 years is 10%. Analyze clinical public data, then determine the relation between metastasis sites and genetic mutation due to survival rate. The number of case data is 956 with OS < 1 year. Principal component analysis of attributes and clinical tests showed the highest contribution rate of MSI-Score as 0.45. The PCA scatter plot of subject attributes and clinical test results is divided into two groups based on genetic test information and metastasis information.