Abstract
To examine the bone disease in uremia, synthetic CO3-apatite with crystallinity and carbonate content similar to those of human bone was incubated in metastable solution. The crystallinity of the CO3-apatite increased with incubation time. Infrared absorption analysis suggested that the recrystallization and/or the substitution of PO43- for CO32- positions occurred. After 3 months incubation, the crystallinity increased with the increase of Ca2+ concentration in the solution, but decreased at high HPO42-concentration. A correlation of these results with bone disease is discussed.
