人工臓器
Online ISSN : 1883-6097
Print ISSN : 0300-0818
ISSN-L : 0300-0818
Dialyzerの生体適合性評価示標としてのbeta-thromboglobulinにかんする検討
芝本 隆松井 則明小沢 潔中村 義弘秋葉 隆吉山 直樹中川 成之輔根本 毅志北岡 建樹
著者情報
キーワード: 血小板, 生体適合性, 透析器
ジャーナル フリー

1981 年 10 巻 1 号 p. 98-101

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抄録
Evaluation method of dialyzer from the viewpoint of biocompatibility currently includes influence on blood corpuscles, activation of complement system, immunological reactions, and so on. As it is not totally systematized yet, there is still a need to find out new parameters. In present study, β-thrombogloburin (β-TG) was studied if it can be a tool of biocompatibility evaluation. Among various membranes tested, β-TG showed a significant elevation after single use of PAN and Cuprophane. As to the difference of binding of hollow fiber, spiral type showed marked elevation. β-TG was only detected in the filtrate of EVA. Thus, β-TG was confirmed as a useful and practical method for evaluation of biocompatibility of dialyzer.
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© 一般社団法人 日本人工臓器学会
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