Molecular Design of Antithrombogenic Polymers

Abstract

In this paper, antithrombogenic surfaces were reviewed, and especially the role of hydrophilic-hydrophobic microphase separated surfaces in polymer-blood interaction was discussed. On the basis of the results obtained from the study on polymer-platelet interaction, we propose that the factor of balance between hydrophilicity and hydrophobicity in macromolecular assembled order is most important to design antithrombogenic polymers.