Basical problems of total artificial heart

(about the structure)

Abstract

Despite of fixed rate pumping, the animal can be alive with total artificial heart for several months. This results suggests that no responce with the change of the venous return seems to be important, particularly on the right side heart.
In other words, the easier way to keep the animal to be alive with total artificial heart may be to cut off the roop of the circulation at the right side heart between the pulmonary artery and the right atrium.
Under these conditions, it is not important whether the natural heart is removed or not, but following characteristics are only required.
1) air-driven sack type pump, or such characteristics.
2) no thrombus formation inside the device.
3) no problems at the natural heart-artificial heart junction.
These conditions are also saticified in our device as others reported so.