Abstract
The polypropylene hollow fiber oxygenator (H. F. O.) was used for open heart surgery in 217 patients. The sizes of 1.6m2, 1.8m2, 3.3m2, two 3.3m2 in parallel and 5.4 m2 were available, one of which was employed for an individual patient depending on the patient body weight.
PaO2, PaCO2 and other gas and hematological data obtained during bypass were within normal range, although the tendency of CO2 retention was recognized in case of more than 2 hrs perfusion.
In the bloodless cardiopulmonary bypass, there were no significant difference in change of hemoglobin value and platelet count during bypass between the patients treated with H. F. O. and bubble oxygena for (B. O.).
In the longer bypass, free water clearance of the kindney was -0.64±0.31cc/fnin/BSA m2 in H. F. O. group (N=7), while it was -0.30±0.24cc/min/BSA m2 in B. O. group (N=13). The difference between two groups was statistically significant, indicating that the kidney function was well preserved in H. F. O, group. When the oxygenator was used in the single pump system, the maximum pressure in the pumping tube frequently exceeded the critical pressure causing hemolysis. However, it was 210±70 mmHg and below the critical pressure in the two pump system.
Therefore it was recommended to use the oxygenator in two pump system. It was observed that kidney function was well preserved by H. F. O. especially in long time perfusion.
