Jinko Zoki
Online ISSN : 1883-6097
Print ISSN : 0300-0818
ISSN-L : 0300-0818
Immunoadsorbent: A Study on the Selective Removal of Immune Complexes in SLE
T. FURUTAN. YAMAWAKIK. INAGAKIM. KATOHT. NIWAK. MAEDA
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JOURNAL FREE ACCESS

1982 Volume 11 Issue 2 Pages 465-467

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Abstract
The specific adsorbents have been sought in an attempt to utilize them for removal of autoantigens, autoantibodies and immune complexes in SLE.
The anion exchangers were broadly investigated for treatment in patients plasma in vitro.
The following results were obtained;
(1) The hydrophiric anion exchangers had large capacities of adsorption of DNA.
(2) The immobilized DNA binded large quantities of anti-DNA antibodies, anti-nuclear antibodies, futhermore, immune complexes.
(3) The anion exchangers, pretreated with heparin, adsorped only partial immune complexes.
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© The Japanese Society for Artificial Organs
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