Experimental of long term intermittent plasmapheresis for myasthenia gravis

Abstract

The patient of 25 year-old female with brittle type MG had been treated by intermittent plasmapheresis for 3 years. The Hemonetics Model 30 was used for plasmapheresis. Plasmapheresis was performed 4-5 times a day for 3 days continuously, and about 6000ml of plasma were exchanged. The immediate effect of plasmapheresis was a rapid fall in Anti-acetylcholine Receptor Antibody level, but about 2 weeks later, antibody titers were recovered to preoperative level. However, after the total of 17 times of plasmapheresis were performed, the patient could be discharged from the Hospital in good conditions.