Abstract
plasma exchange is now widely applied in clinical practice utilizing membrane plasma separators with vrious membrane materials and modules such as hollow fiber and disc membrane. performances of plasma separation and solutes transfer have been examined in five currently obtainable plasma separators i. e., Plasmaflo, Plasmaflux, Plasmax, Plasmacure and Trumo---.
The filtration rate varies from 26.5±2.8ml/hr.mmHg to 120.2±2.5ml/hr.mmHg among the separators. The sieving coefficients exceed 0.9 even for large molecules such as IgM in all separators examined. Therefore, it is concluded that the performance of all plasma separators is satisfactory for present plasma exchange modality where three to four liters of plasma is treated per procedure.
