Development of Control Method of Total Artificial Heart (TAH): A trial of neural Control with Electrical Stimulation and its Effects

Abstract

The development of TAH control mehod is not yet perfect, and slight anemia, increase in CVP and other abnormal phenomena are observed in experimental animals. One of the cause of these phenomena is thought to be a lack of afferent nerve discharge from cardiac receptors. In this study, electrical stimulation was given to the goats whose heart had been substituted with AH. The surviving state of goats were much improved by the electrical stimulation. The results show that neural control i s inevitable for TAH control, in addition to blood pressure and blood flow rate.