Cardiopulmonary Restriction Caused By Partial Veno-arterial Extracorporeal Lung Support In Dogs

Abstract

Changes in cardiopulmonary functions were studied in 14 dogs underwent partial venoarterial extracorporeal lung support (30% of C. O.) for 3 (group I), 6 (group II). and over 28 hours (group III). Under air breathing, blood gases, A_aDo₂, and Qs/Qt did not change after the experiments, whereas pure oxygen breathing revealed increase in A_aDo₂ in group l and III, In group I postoperative D_LCO decreased for a week and then recovered. Time course of static lung compliance was also likely. P_PA, C. O. and TPVR did not change in all groups. We conclude that partial perfusion does not cause severe restriction of cardiopulmonary function but a little lasting for a week.