Beneficial Effects of Continuous Peritoneal Dialysis in the Treatment of Severe Acute Pancreatitis

Abstract

Peritoneal dialysis were performed to 3 patients with severe acute pancreatitis which were clsified into severe group by Ranson's positive score. They were treated with excellent success. One of them was found that pseudo-pancreatic cyst disappeared after continuous peritoneal dialysis by abdominal Ct. Amylase clearances of peritoneum in the active period of acute pancreatitis were 3.9+1.0ml/min(M+SE) as much as 14 times of the peritoneal clearance in CRF patients without peritonitis. These results are seemingly suggestive that amylase removed not only by concentration gradient but also by directly spilling effect into dialysate from retroperitoneal cavity. Pertoneal dialysis might be an extremely effective adjunct to management of acute severe pancreatitis with Ranson's high score.