Clinical effects of continuous bicarbonate hemofiltration

Abstract

To treat the ureinic patients with multi-organ failure, we performed continuous hemofiltration(CHF) with minimum sized hemofilter (PAN-30, Asahi) and newly developed bicarbonate substitution fluid. CHF had sufficient capacity to remove uremic substrates and fluid, and to correct the electrolyte and acid-base disturbances. CHF showed dramatic effects on severe lung edema, hepatic failure, lactic acidosis and so on. These results indicate that CHF is preferable therapeutic procedure to treat the severe patients with multi-organ failure.