無ヘパリン化体外循環の研究 ―prostacyclin誘導体単独投与とヘパリン単独投与の比較―

高浜 龍彦; 須藤 憲一; 小塚 裕; 和気 一夫; 川内 基裕; 横井 泰; 水野 明; 浅野 献一; 風間 睦美; 森岡 真知子; 岩田 久恵; 苑田 毅; 西尾 伸太郎; 大野 清隆; 丹沢 宏

doi:10.11392/jsao1972.14.1548

Study on non-heparinized cardiopulmonary bypass

-Comparison between CPB using pros tacyc i l i n analogue alone and heparin alone

T. TAKAHAMA, K. SUDO, Y. KOTSUKA, K. WAKE, M. KAWAUCHI, Y. YOKOI, A. MIZUNO, K. ASANO, M. KAZAMA, M. MORIOKA, H. IWATA, T. SONODA, S. NISHIO, K. OHNO, H. TANZAWA

Author information

T. TAKAHAMA
Dep of Thorac Surg, Univ of Tokyo
K. SUDO
Dep of Thorac Surg, Univ of Tokyo
Y. KOTSUKA
Dep of Thorac Surg, Univ of Tokyo
K. WAKE
Dep of Thorac Surg, Univ of Tokyo
M. KAWAUCHI
Dep of Thorac Surg, Univ of Tokyo
Y. YOKOI
Dep of Thorac Surg, Univ of Tokyo
A. MIZUNO
Dep of Thorac Surg, Univ of Tokyo
K. ASANO
Dep of Thorac Surg, Univ of Tokyo
M. KAZAMA
Teikyo Univ.
M. MORIOKA
Teikyo Univ.
H. IWATA
Teikyo Univ.
T. SONODA
Teikyo Univ.
S. NISHIO
Toray Ind. Co.
K. OHNO
Toray Ind. Co.
H. TANZAWA
Toray Ind. Co.

Keywords: Prostacyclin, heparin, cardiopulmonary bypass, platelet

JOURNAL FREE ACCESS

1985 Volume 14 Issue 3 Pages 1548-1551

DOI https://doi.org/10.11392/jsao1972.14.1548

Details

Abstract

Prostacyclin analogue enabled CPB protecting platelet by reversible inhibitory effect on platelet aggregation, but caused some promotion of blood coagulation and fibrinolysis. Heparin proved to inhibit blood coagulation system completely, but caused much damage on platelets.

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