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[in Japanese]
1985 Volume 14 Issue 3 Pages
1055
Published: June 15, 1985
Released on J-STAGE: October 07, 2011
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-Evaluation of mechanical work of left ventricle-
T. NAKAMURA, K. HAYASHI, J. SEKI, T. NAKATANI, Y. TAENAKA, H. NODA, H. ...
1985 Volume 14 Issue 3 Pages
1057-1060
Published: June 15, 1985
Released on J-STAGE: October 07, 2011
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Mechanical work of left ventricle during cardiac assist was studied by acute
in vivo experiments on mongrel dogs with normal hearts under five driving modes. Newly developed 8-channel ultrasonic displacement meter was utilized to determine left ventricular diameter and regional muscular length. The left ventricular mechanical work was calculated from the displacement data and left ventricular pressure. The whole left ventricular work as well as the regional muscular work under any pumpingg modes were reduced significantly by the left ventricular assist, maximally under asynchronous modes and followed by under 2:1 synchronous mode.
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C. M. WEI, M. IMURA, R. HATTORI, K. SAITO, K. MIYAMURA, M. FUKUYAMA, M ...
1985 Volume 14 Issue 3 Pages
1061-1064
Published: June 15, 1985
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Right ventricular (RV) functions during left heart bypass using centrifugal pump were studied in fourteen mongrel dogs They were devided to two groups of normal heart and failing heart RV functions were evaluated hemodynamically and by twodimensional echocardiography (2D-Echo). Incremental increases in LHB flow ratio (LHB flow×100/LHB flow+ascending aortic flow) to 25%, 50%, 75% and maximum flow (about 85-100%) were associated with decrements in interventricular septum (IVS) segmental shortening fraction (SSF) from 54±12% in control, to 43±5%, 42±2%, 35±7% and 0%, respectively. Increasing LHB ratios resulted in decreasing LVED volume and concomitant increased RVED volume decreasing heart rate; increasing RV stroke volume and RV stroke work. When LHB ratio increased from 75% to maximum, the significant reduction in RV ejection fraction (cross sectional area by 2D-Echo) and completely decompressed LV were observed. And also the cross sectional echocardiographic image revealed profoumdly depressed SSF of IVS and RV free wall nearby. Decompressed LV by LHB with maximum flow seemed to decrease the LV wall motion including IVS, that caused to reduce the efficiency of RV contraction Therefor 75% bypass ratio during left heart bypass is more than maximum flow ratio with LV decompression.
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-Evaluation by left ventriculography (LVG)-
T. NAKATANI, H. TAKANO, H. NODA, T. TANAKA, S. FUKUDA, M. UMEZU, A. NO ...
1985 Volume 14 Issue 3 Pages
1065-1068
Published: June 15, 1985
Released on J-STAGE: October 07, 2011
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The acute LVAD experiments (left atrium-aorta) were performed in six mongrel dogs to evaluate the natural heart movement by LVG. In normal condition, with LVAD on, LV end-diastolic volume (LVEDVI), stroke volume (SVI), stroke work (SWI), LV work (LVWImin) and wall stress decreased to 68, 31, 42, 43 and 80% of the LVAD off values. While in the failing heart, when LVAD was on, LVEDVI, SVI SWI, LVWImin and wall stress at asynergy decreased to 72, 51, 74, 71 and 69% of LVAD off values. In conclusion, LVAD can effectively decrease volume load, work and wall stress of the natural heart.
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K. NISHIGAKI, H. HIROSE, H. MATSUDA, S. NAKANO, R. SHIRAKURA, M. OHTAN ...
1985 Volume 14 Issue 3 Pages
1069-1072
Published: June 15, 1985
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Sixteen mongrel dogs were injected the following three vasodilators during left heart bypass. 1. tolazoline (Tz) 2mg/kg. 2. PGI
2 analogue (PG) 1γ/kg 3. isoproterenol (ISP) 0.1γ/kg/min. Tz decreased SVR and PVR, and increased RV output stastically. PG increased RV output, and decreased SVR and PVR. The injection of ISP was inclined to decrease SVR and PVR, and to increase RV output. Thus the administration of vasodilators during left heart bypass is effective-to increase RV output and may improve the peripheral perfusion.
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Y. ORIME, A. YAMAZAKI, A. MIYAMOTO, M. SHIONO, K. OGASAWARA, Y. NAMIKI ...
1985 Volume 14 Issue 3 Pages
1073-1076
Published: June 15, 1985
Released on J-STAGE: October 07, 2011
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Hemodynamic effectiveness, especialy coronary sinus flow, of mechanical circulatory assistance (IABP, LVAD) was evaluated agaist acute left ventricular failure in swine.
The result of experimental study, hemodynamic changes in IABP alone was not satisfactory, but LVAD revealed useful assist for left ventricular failure. However combination method pith IABP (counterpulsation method) and LVAD (fixed rate method) showed almost same hemocynamic effectiveness of LVAD (counterpulsation method) alone.
Moreover, in this combination method, coronary sinus flow and renal artery flow were decreased, and this method was thought to be not appropriate.
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T. NAKATANI, H. TAKANO, T. TAENAKA, M. UMEZU, H. NODA, T. TANAKA, H. I ...
1985 Volume 14 Issue 3 Pages
1077-1081
Published: June 15, 1985
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In order to evaluate the biological responses to LVAD pumping, LVAD was applied to goats and mongrel dogs that were induced with left ventricular failure (LVF) by multiple ligations. Total Flow (cardiac output+bypass flow), AoP, systemic vascular resistance and myocardial tissue blood flow were maintained within normal range by LVAD pumping. Left ventricular end-diastolic volume, stroke volume, stroke work and ejection fraction were markedly decreased by LVAD pumping. In chronic experiments, however, there were no noticeable changes in biochemical study. So LVAD can maintain normall circulation even in profound LVF.
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[in Japanese]
1985 Volume 14 Issue 3 Pages
1082
Published: June 15, 1985
Released on J-STAGE: October 07, 2011
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K. SOEJIMA, K. AKIYAMA, S. FUKUCHI, Y. TAKANASHI, M. ENDO, H. KOYANAGI
1985 Volume 14 Issue 3 Pages
1083-1086
Published: June 15, 1985
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ASSIST CIRCULATION (V-A BYPASS & L-V BYPASS) Between Jan. of 1981 and May of 1984, 163 cases which were performed the assist circulation following 1623 open heart operations. In 132 of 163 cases only IABP were performed, and 112 (84.8%) cases of them could be weaned from IABP. Six (23.1%) of 26 cases performed V-A bypass could be weaned from bypass. Three (60%) of 5 cases performed L-V bypass could be weaned from bypass. In cases of successful weaning from V-A bypass, the longest duration of bypass was 430min.. While, in cases of successful weaning from L-V bypass, the longest duration of bypass was 6660min. Hence, improving the L-V bypass system, we will aggressively perform the L-V bypass.
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H. NAKAHARA, T. IMAZEKI, M. SUNAMORI, A. SUZUKI
1985 Volume 14 Issue 3 Pages
1087-1090
Published: June 15, 1985
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Evaluation of hemodynamic and metabolic effect of left ventricular bypass (left atrium to aorta) was made on normal heart and quantitative failing heart produced in 6 mongrel dogs by injection of 5N-NaOH. In failing heart group, left ventricular end-diastolic pressure (LVEDP) was higher than in normal heart group, As a result of higher LVEDP, more effective volume unloading of left ventricular was abtained in failing heart group. Evaluation of exygen comsumption of myocardium and myocardial lactate extraction ratio suggested more effective protection of myocardium in failitig heart group than in normal heart group.
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H. TAKAGI, T. TAKAGI
1985 Volume 14 Issue 3 Pages
1091-1094
Published: June 15, 1985
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Modification of 1-atrio and 1-ventricular---aortic bypass (Combination bypass): In our original methode of combination bypass, 2 inflow ducts were independently connected to the 1 atrium and the 1 ventricle respectively. These ducts were adherered together in one duct, and inserted through the 1 auricle, though their inflowing way were separated by septum. On hemodynamic effects by pumping, total left heart bypass and the complete unloading of the 1 ventricle were constantly obtained.
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N. UCHIDA, Y. KAGAWA, T. HONGO, M. MIURA, K. URAYAMA, S. NITTA, Y. KAT ...
1985 Volume 14 Issue 3 Pages
1095-1098
Published: June 15, 1985
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Six dogs received the atrial cannulations, 3 in right and 3 in left. Putting to death 10 to 14 days after operation, the lung, kidney and atria were examined macro and microscopically. Finding of these sepcimen showed no thromboembolisms nor infectious glannulations. Inner part of the cannula was filled with clots. In conclusion, atrial cannulae can be left within atria for 10 to 14 days without the risk of thromboembolism or infection untill the patient's hemodynamics are stabilized. With carefull technique, the cannulae can be removed without the clots letting fall into the atria.
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Masahiro ENDO, [in Japanese], [in Japanese], [in Japanese], [in Japane ...
1985 Volume 14 Issue 3 Pages
1099-1102
Published: June 15, 1985
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In cases where IABP can not be performed unlimitedly to assisted circulation, a V-A bypass and a left heart bypass. The authors developed two new devices. (1) One device was used when an infusion cannula was inserted percutaneously into the femoral artery by the Seldinger method. (2) The other device was used to a detachable cannula inserted into the right or left atrium from the respective atrium without performing open thorabotomy when the inserted cannula was required to be held no more.
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[in Japanese]
1985 Volume 14 Issue 3 Pages
1103
Published: June 15, 1985
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F. IWAI, Y. UMEZU, S. SUZUKI, H. IMAMURA, S. TAKEUCHI, T. INOUE
1985 Volume 14 Issue 3 Pages
1104-1107
Published: June 15, 1985
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Hemodynamic property of the system was examined. Then the quality of the pulsatile device was tested by twelve mongrel dogs. Results are as follows: (1) pulsatile flow of 2.5l/min was obtained (2) left atrial mean pressure decreased 4.2mmHg and left ventricular systolic pressure 19.6mmHg with the 80% assist (3) pressure augmentation was shown when the flow was driven in diastolic phase (4) backward flow from aorta to this system was not observed although there were no valves in this system.
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I. YADA, K. MIYAMURA, K. SAITO, C. M. WEI, R. HATTORI, M. KUSAGAWA
1985 Volume 14 Issue 3 Pages
1108-1111
Published: June 15, 1985
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We evaluated the effectiveness of a centrifugal left ventricular assist device in dogs with acute myocardial infarction and in unanesthetized goats with normal heart. Pulse pressure decreased half of normal at 50% and was gone nonpulsatile flow at 100% left ventricular bypass. RV output and renal blood flow increased following increasing left ventricular bypass flow. But carotid blood flow was no significant change. TTI reduction decreased in 25.6+11.2% at 50% and 52.3+21.3% at 100% LV bypass respectively. Serum cathecholamine levels and renal functions remained normal. These data indicate no untoward effects as a result of prolonged nonpulsatile perfusion.
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S. HASHIMOTO, H. ASARI, Y. MATSUYAMA, A. ISHIHARA, K. MABUCHI, H. SUZU ...
1985 Volume 14 Issue 3 Pages
1112-1115
Published: June 15, 1985
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The hydrodynamic effect on hemolysis in a centrifugal pump was investigated by animal tests and in vitro tests. First, a magnetically driven centrifugal pump was manufactured as an artificial heart and used for right ventricular bypass or biventricular bypass on the canine (body weight: 15-28kg) heart. Secondly, the same pump was used to canine blood circulation tests in vitro. Thirdly, the cone and cup type of testing machine was used to give constant velocity gradient (max. 1100sec
-1) to the whole canine blood sample. The results show that the hemolysis rate tends to increase as the rotational speed of the impeller of the centrifugal pump increases and that the hemolys is rate is less than 10
-3 hour
-1 at the velocity gradient less than 2×10
2 sec
-1.
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Y. YAMADERA, [in Japanese], [in Japanese], [in Japanese], [in Japanese ...
1985 Volume 14 Issue 3 Pages
1116-1119
Published: June 15, 1985
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Energy loss in aortic return cannula for extracorporeal circulation. The influence of arterial line and cannula size on blood pressure and flow at the aortic root was studied using our mock circulatory system which can allow changes of cannula size (10-22F) and pump type (Bio-pump, roller pump, pneumaticallydriven pulsatile pump). As a result, a largest size cannula available must be used to obtain larger pump flow and to reduce energy loss when using a Bio-pump or a roller pump. The tube length and diameter do not have a great influence on pump output. In case of a pulsatile pump, the difference of cannula size and drive pressure has a big effect on cardiac output and aortic pressure wave form, while a care must be paid with respect to inserting angle of the return cannula.
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M. UMEZU, H. NODA, A. NOGAWA, T. NAKATANI, T. YOSHIWARA, Y. YAMADERA, ...
1985 Volume 14 Issue 3 Pages
1120-1123
Published: June 15, 1985
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L and S type two aluminium molds, whose sizes matched 25 and 21 ABP of the Björk-Shiley (BS) valves, respectively, were developed and used to fabricate one-piece conduit type PU valves. In-vitro test data of pump flow, pressure gradient and effective orifice area for L type valves suggested that leaflet thicknesses of 0.20mm and 0.32mm in the inlet and outlet, respectively, result i n the optimal valve performance. As, for the S type valves, the valve with 0.40mm leaflet thickness lead to undesirable pump performance, while usage of 0.26mm valves gave comparable performance as that of the BS valves.
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[in Japanese]
1985 Volume 14 Issue 3 Pages
1124-1125
Published: June 15, 1985
Released on J-STAGE: October 07, 2011
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S. TANAKA, K. YAMAKOSHI, A. KAMIYA, H. TAJIMA, Y. YOKOYAMA, M. KUSAKAB ...
1985 Volume 14 Issue 3 Pages
1126-1129
Published: June 15, 1985
Released on J-STAGE: October 07, 2011
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A seal-less centrifugal blood pump for the use of extracorporeal circulation was newly designed. A cylindrical rotor connected with a impeller (with 6 blades) in a blood-casing was magnetically floated by three pairs of cylindrical floater-magnets. The rotor also fixed with a cylindrical rotor-magnet was driven by an armature located around a housing of the pump. Thus, the impeller could be rotated without bearings and seals over a wide range of rotating speed (0-4 krpm) by magnetically transmitted force. In vitro experiments concerning the pump function and hemolysis were made using four different configurations of the impeller. The most appropriate configuration of the impeller with inlet and outlet blade angles of 90° and 50°, respectively, was obtained with regard to the pump characteristics and hemolysis. Considering the simplicity and disposability of the pump unit, the present pump seems to be more practicable and advantageous compared with commercially available centrifugal-type blood pumps.
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T. SHIROYAMA, T. AKAMATSU, F. BETTUPU, H. FUKUMASU
1985 Volume 14 Issue 3 Pages
1130-1132
Published: June 15, 1985
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A centrifugal pump with a nutating impeller is called tea-spoon type pump. Aiming at improvement of efficiency, we invented a new-type TS pump. A spherical-cone impeller nutates, as if a piston moves in an endless cylinder, in the annular passage between the inside of casing and the outside of inlet portion. Initially we made a simplified two-dimensional model of that pump and investigated the relasions of pump performance to the following items: shapes and dimensions of casing, inlet- and outlet-portions, an impeller and the annular passage. The casing with swelling ahead of the outlet proved to be better than the circular casing. Referring to the above-mentioned results, we made and investigated a new-type TSpump of three-dimensional structures. Preliminarly experiments showed that the obtained pressure and efficiency were about 60% of the two-dimensional model, this was maybe caused by decrease in the effective piston area of the impeller. Hereafter, we intend to improve its characteristics by changing shape and clearance of the annular passage.
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T. YOSHIHARA, [in Japanese], [in Japanese], [in Japanese], [in Japanes ...
1985 Volume 14 Issue 3 Pages
1133-1136
Published: June 15, 1985
Released on J-STAGE: October 07, 2011
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Effects of artificial heart drive conditions on water hammer phenomenon that usually occurrs at the vicinity of the artificial valves were studied using three types of Mock Circulatory System which simulate the in vivo situations of TAH, LVAD, pulsatile ECC. Results showed: 1) The peak pressure gradient across the valves (PPG) was found to be largest when the pump was operated at its full stroke; it decreased with reduction in pump stroke. 2) The occurrence of valve fracture showed strong correlation with the level of PPG across the valve. 3) Since the level of water hammer depends on the valve type, selection of valves used in artificial heart studies is a key to reduction in the valve fracture.
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S. KOBAYASHI, H. TAKAHASHI, H. NISHIYAMA, H. ITOH, Y. SUENAGA, C. KATO ...
1985 Volume 14 Issue 3 Pages
1137-1140
Published: June 15, 1985
Released on J-STAGE: October 07, 2011
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A new roller-type pulsatile blood pump has been developed. It was driven by a DC servo motor, which has been controlled by a microcomputor and transistor chopper system. A pulsatile blood flow can be delivered by regulating the on-time and rotation speed of the rollers in the pump. Hydrodynamic studies were performed using model circuit systems to evaluate its characteristics.
(1) The actual output of the pump was measured under each programmed flow rate by changing the pulse rate from 40 to 140 pulses per minute. The deviation of the actual output were 4.5% at 1liter/min, 3.6% at 2liter/min, 4.8% at 3liter/min and 6.4% at 4liter/min on the average.
(2) Pressure and flow curve patterns were examined and recorded by changing the period of the on-time, under fixed pulse rate (75/min) and flow rate (2liter/min). It has been revealed that the shorter the on-time, the steeper the rise of each curve.
(3) By changing the pulse rate as 40, 75, 96 and 125/min, it has been confirmed that the responsibility of this pump was faithful corresponding with the change of pulse rates even under high-speed driving.
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[in Japanese]
1985 Volume 14 Issue 3 Pages
1141
Published: June 15, 1985
Released on J-STAGE: October 07, 2011
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-Comparison of medical theraphy and surgical theraphy-
H. YAMANAKA, S. KYO, H. ADACHI, S. TAKAMOTO, Y. YOKOTE, R. OMOTO
1985 Volume 14 Issue 3 Pages
1142-1145
Published: June 15, 1985
Released on J-STAGE: October 07, 2011
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To evaluate the effect of mechanical circulatory support (IABP, VAB), we examined a series of 34 patients (pts) with an extensive AMI. 17 pts were treated conservativelly with IABP support. 15 pts (8.8%) were died without separating from the IABP support. In 17 pts who were treated surgically with IABP support, we could save 11 pts (65%) with successful separation from IABP. Thus, only an immediate surgical theraphy combined to mechanical circulatory support save the life of cardiogenic shock patients due to AMI.
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T. YOKOSAWA, H. OHZEKI, H. OKAZAKI, M. NAKAGOMI, J. HAYASHI, S. OHTANI ...
1985 Volume 14 Issue 3 Pages
1146-1149
Published: June 15, 1985
Released on J-STAGE: October 07, 2011
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During last six years and four months in our institute, 216 cardiac valve replacements were performed, and 18 of them (8.3%) required IABP postoperatively. Twelve of them were male, six of them female, the mean age was 52 years old. 10 out of 18 IABP cases (55%) survived. Seven cases necessitated IABP because they could not be weaned from cardiopulmonary bypass. Five of them could get off from IABP, but three cases died of MOF after the removal of IABP. IABP was indicated for eleven cases because of LOS after cardiopulmonary bypass weaning, and eight of them survived, three died of heart failure without weaning. Severe low cardiac output level was observed in some cases even after IABP, therefore more effective cardiac support is desirable.
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T. TASHIRO, H. NAKAMURA, K. TODO, Y. OKITA, A. ORYOJI, K. KOSUGA, K. O ...
1985 Volume 14 Issue 3 Pages
1150-1153
Published: June 15, 1985
Released on J-STAGE: October 07, 2011
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The purpose of this paper is to present the usefulness and limitations of the intraaortic balloon pum ping (IABP) in the management of acute myocardial infarction without mechanical defect.
We treated 15 cases with IABP, 11 of which weaned from IABP and survived. IABP produced effective hemodynam is changes in almost all the cases without significant complication, but could not salvage all the cases. We conclude that early use of IABP and additional coronary reperfusion therapy (PTCR or CABG) if necessary are usefull in the management of severe patient with acute myocardial infarction.
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M. YAMADA, T. TAKABA, T. MICHIHATA, M. FUNAMI, J. ISHII, T. MIYA, K. M ...
1985 Volume 14 Issue 3 Pages
1154-1157
Published: June 15, 1985
Released on J-STAGE: October 07, 2011
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We have reviewed our 1981 to 1984 experience with intraaortic balloon pumping (IABP) in 34 consecutive patients to evaluate the indication and the efficacy of IABP. Among the 166 patients underwent prosthetic valve replacement, 23 patients (Group I) were treated with IABP postoperatively. Among the 74 patients performed surgery for ischemic heart disease, 11 patients (Group II) were treated with IABP. Nineteen (83%) were weaned from IABP and 17 (74%) were discharged in Group I. Eight (73%) were weaned from IABP and six (55%) were discharged in Group II. Acute renal failure (ARF) was 30% in Group I and was 36% in Group II. IABP was effective for LOS not only in prosthetic valve surgery but also in surgery for ischemic heart disease.
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[in Japanese]
1985 Volume 14 Issue 3 Pages
1158
Published: June 15, 1985
Released on J-STAGE: October 07, 2011
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Y. OKAMOTO, T. BAN, S. NOMOTO, H. FUKUMASU, H. NAGAMI, A. AWAZU
1985 Volume 14 Issue 3 Pages
1159-1161
Published: June 15, 1985
Released on J-STAGE: October 07, 2011
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With the development of pediatric IABP reference data on the internal diameters of the descending aorta are essential. Measurements were made by cineangiography. The data revealed linear correlations between the internal diameters of the descending aorta and body length. In five patients who were from 6 months to 5 years after surgery IABP was used. In all patient was there appreciable effect of IABP. Miniaturization of the equipment has permitted IABP to be used effectively in pediatric patients.
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Y. KASAGI, M. YOKOYAMA, T. ITAOKA, H. NAGARA, J. WADA
1985 Volume 14 Issue 3 Pages
1162-1164
Published: June 15, 1985
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The authors attached ECG electrodes to the IABP catheter. These electrodes allow monitoring of the ECG and immediate start of ECG triggered IABP. This catheter improve enabled effective and comprication free IABP.
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[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...
1985 Volume 14 Issue 3 Pages
1165-1168
Published: June 15, 1985
Released on J-STAGE: October 07, 2011
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by Masahiro Endo et al. Conventionally, it has been indicated that IABP should be performed after the occrrence of LOS and shock. At present, IABP is carried out actively as a preventive step or a procedure of a scheduled treatment program in the pre-stage before LOS or sghock takes place. The authors applied IABP to 181 cases of open heart surgery. Before the operation, a 19G plastic needle was inseated percutaneously into the femoral artery, and only its outer sheath fixed on the skin in each case. It was necessary to insert IABP in 31 cases. IABP could be inserted actually in 30 cases. The usefulness of the “pending stand by” method developed by the authors is mentioned.
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T. TAKABA, T. MICHIHATA, M. KADOKURA, J. ISHII, K. MORIMOTO, T. MIYA
1985 Volume 14 Issue 3 Pages
1169-1172
Published: June 15, 1985
Released on J-STAGE: October 07, 2011
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Ten patients treated with intra aortic balloon pumping (IABP) and hemodialysis after cardiac surgery were reported. Nine patients were weaned from IABP. However, only 5 of 9 patients could not be weaned from hemodialysis. Acute renal failure after cardiac surgery might be caused by low cardiac output syndrome, which was successfully improved by IABP in 9 patients in our series. However, multiple organ failure including gastrointestinal bleeding, hepatic failure and severe infection was clinically detected during hemodialysis treatment. In our series, the long term survival rate ranged into 40%, 4 out of 10 cases.
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M. MATSUDA, K. HIRATA, K. NISHIMURA, M. HANADA, T. TAKEUCHI, T. ODA, M ...
1985 Volume 14 Issue 3 Pages
1173-1176
Published: June 15, 1985
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IABP---Clinical results and study of death cases. Since 1977, IABP was clinically used in 246 patients (including 4 children) of ischemic, valvular or congenital heart disease. Thirty five patients were treated medically and surgical repair were performed in 211 patients. IABP was begun under the condition of 1) cardiogenic shock 2) electromechanical dissociation, 3) intractable arrhythmia in case of acute myocardial infarction, 4) LOS at the operation, 5) vasospastic anginal attack during or after surgery, and 6) operation of the patients with hepatic, renal and/or ventricular hypofunction. Mortality rate was 36.2% (=89/246) and the causes of death were studied.
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[in Japanese]
1985 Volume 14 Issue 3 Pages
1177
Published: June 15, 1985
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N. KABEI, K. TSUCHIYA, Y. SAKURAI
1985 Volume 14 Issue 3 Pages
1178-1181
Published: June 15, 1985
Released on J-STAGE: October 07, 2011
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Dynamic pericardium pumping (DPP) for partial biventricular assistance. Dynamic pericardium, consisting of two balloons which are inserted into the pericardial cavity, was developed to squeeze out blood from the ventricles which have less or no functions. Optimal driving conditions were investigated. They are as follows: driving air pressure=0.5Kg/cm
2, pulse rate=110bpm and sytolic duration=195ms. During partial assistance the hemodynamic value was maintained almost control values.
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T. HONGO, Y. KAGAWA, S. NITTA, N. UCHIDA, M. MIURA, A. KATAHIRA, M. TA ...
1985 Volume 14 Issue 3 Pages
1182-1185
Published: June 15, 1985
Released on J-STAGE: October 07, 2011
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Histrogical examination of inner surface of right ventricular pulsatile patch coatedd with Avcothane and interal organs of a goat, which survived 10 months after operation were carried out. Gross findings revealed no evident clots nor calcium deposi tes. In electron microscopic examination inner surface was covered with thin protein membrane with several masses of platelets 100 microns in maximum size. EPMA examination revealed no calcium or phosphorous elements within wall of patch. There were no pulmonary emboli in gross and microscopic findings. Slight cirrhotic changes were noted in liver.
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Y. YOSHIOKA, K. SASAHARA, M. KITAMURA, M. MISUMI, H. KUROSAWA, H. KOYA ...
1985 Volume 14 Issue 3 Pages
1186-1189
Published: June 15, 1985
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Experimental study of intraventricular balloon pumping (IVBP). We examined IVBP to provide circulatory support. Experimental dogs were used with the IVBP inserted via the apex of the heart. The pumping was accompanied by an increase in systolic BP, CO and a decrease in LAP, when the CO of the unassisted heart was under 50% of normal heart. It was found that when the heart was normal, the IVBP was not effective, and also not effective in generating a peripheral blood flow while the heart was fibrillaing. Cases of arrhythmia induced by IVBP were very few. In clinical practice, IVBP will be inserted from a peripheral artery such as IABP to decrease infection and bleeding.
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J. MIYA, H. MAETA, M. HORI
1985 Volume 14 Issue 3 Pages
1190-1193
Published: June 15, 1985
Released on J-STAGE: October 07, 2011
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Hemodynamic effects of a newly devised EPABP were evaluated experimentally in normal and experimental animals with pulmonary regurgitation (PR) and resulted acute right heart failure. In normal group (n=9), the EPABP brought increase in CO by 3.9% with elevation of mean PAP and AoP and drop of mean RVP. On the other hand, in PR group (n=7), the EPABP elevated diastolic and mean PAP and mean AoP by 7.9mmHg, 2.3mmHg and 4.1mmHg respectively, producing increase in CO by 10.1%.
These effects might be based on (1) increase in pulmonary arterial forward flow in diastole, (2) early systolic unloading of RV, and, in case of PR, (3) prevention of pulmonary regurgitation.
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H. TAMURA, A. YAMAGUCHI, M. OHTAKI, C. NOJIRI, T. MINOJI, N. ATOBE, N. ...
1985 Volume 14 Issue 3 Pages
1194-1197
Published: June 15, 1985
Released on J-STAGE: October 07, 2011
JOURNAL
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Clinical experiences and considerations of Intraaortic Balloon Pumping and Intrapulmonary Balloon Pumping
IABP is more effective for left heart failure after open heart surgery. Especially IABP is most applied in ischemic heart disease. However, the indications and timing of IABP have been contravesial. We have used IABP after undergone valve surgerys (18/273=7.6%). Out of 18 cases, 11 cases have meaned from IABP successfully, and 8 cases have been survived for a long time (44%). Indications of IABP were divided into 4 groups according to each pathological consideration. Group I includes in penioperative LOS, group II in insufficiency of diastolic filling, group III in preoperative LOS, group IV in miscellaneous type. The result of group III was satisfactory, but group I and II were less effective for IABP.
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[in Japanese]
1985 Volume 14 Issue 3 Pages
1198
Published: June 15, 1985
Released on J-STAGE: October 07, 2011
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-From the point of peripheral circulation-
K. MIYAMURA, K. SHIKANO, H. SHINPO, M. NASU, S. SHOMURA, I. YADA, M. K ...
1985 Volume 14 Issue 3 Pages
1199-1201
Published: June 15, 1985
Released on J-STAGE: October 07, 2011
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The newly developed electromechanical left ventricular assist device was characterized in failing heart dogs. The left renal arterial and left common carotid arterial blood flowa were measured by electromagnetic flow probe to evaluate the peripheral circulation. Authors observed that 2L/min LV-Ao bypass flow improved the circulatory condition and 1-2ml/Kg/hr of urinary output was maintained. This bypass flow was equal to 75% of the normal cardiac output. So it would be good enough for the peripheral circulation if the left ventricular assist device could bypass 75% of the normal cardiac output.
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E. NAKAYAMA, N. KABEI, S. IIJIMA, Y. SAKURAI, K. TSUCHIYA
1985 Volume 14 Issue 3 Pages
1202-1205
Published: June 15, 1985
Released on J-STAGE: October 07, 2011
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Development of Polarized Electromagnet Driven Blood Pump. A Polarized electromagnetic energy conversion system with a rare earth magnet was chosen as a power souce. The mechanism to magnify the stroke of an armature by a link connected to a pusher plate were designed. A bench test model of this mechanism was assembled. Measuring devices to analyze the dynamic characteristics of the system were developed. The dynamic characteristics of this pump were examined in the mock circulatory system. The efficiency of this pump from the electric energy to mechanical work was 28% and that from the electric energy to fluid energy was 22%. The energy loss of this pump was mainly due to malfunction of the electromagnet and miss matching between the magnet and the load springs.
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T. MURAYAMA, N. KABEI, H. IMAI, A. NODA, K. TSUCHIYA, E. SHIMEMURA, Y. ...
1985 Volume 14 Issue 3 Pages
1206-1209
Published: June 15, 1985
Released on J-STAGE: October 07, 2011
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The basic design of our portable driving unit follows that of an ordinary and stationary one. But for making it portable, we developed a mechanism which directly controlled the compressor by feeding back the level of the pressure in the air tank. On that concept, we made the first prototype driving unit, which had Ni-Cd battery, A linear compressor, and two flexible air tanks. The size of this driving unit was 150×300×500[mm], and its weight was about 15[Kg]. From in vitro experiment, we knew this unit could generated 6[L/min] blood flow, it could make the same air wave form which the stationary unit made, it could be operated for 2.5 hours under those conditions.
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I. FUJIMASA, K. IMACHI, M. NAKAJIMA, K. MABUCHI, T. CHINZEI, Y. ABE, K ...
1985 Volume 14 Issue 3 Pages
1210-1213
Published: June 15, 1985
Released on J-STAGE: October 07, 2011
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A new type mechanical driven blood pump with an atrium and a ventricle has been designed and developed. Three designing requirements must be fulfiled for this pump. (1) Atrio-ventricular septal wall is actuated to drive. (2) A valve is inserted in the passage between the atrium and the ventricle. (3) A valve should be installed in the outflow conduit. Through our designing competition, two prototype model were developed and evaluated in vitro testing.
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N. SATO, H. HARASAKI, J. SNOW, W. SMITH, Y. SUGITA, S. MATSUSHITA, S. ...
1985 Volume 14 Issue 3 Pages
1214-1217
Published: June 15, 1985
Released on J-STAGE: October 07, 2011
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Effects of the heat on systemic organ functions and the local tissue were evaluated in 6 calves which survived 7-53 days with heat generating LVAS and compared to 6 controls. No systemic effects were noted except for slight incerease of the body temperature. The tissue capsule tended to be thicker with dilation of the capillaries and angioneogenesis. PNI formed on the heated surface was acellular and required longer tine to be stabilized.
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[in Japanese]
1985 Volume 14 Issue 3 Pages
1218
Published: June 15, 1985
Released on J-STAGE: October 07, 2011
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Y. SUZUKI, Y. MITAMURA, E. OKAMOTO, J. SASAHARA, T. SHIMOOKA, T. MIKAM ...
1985 Volume 14 Issue 3 Pages
1219-1222
Published: June 15, 1985
Released on J-STAGE: October 07, 2011
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We have developed control system for assist pump, which realizes automatic control of arterial and atrial pressure. Control system regulates an arterial and atrial pressure by adjusting a driving pressure proportion to the difference between desired pressure and noninvasively measured pressure.
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S. NITTA, Y. KATAHIRA, M. TANAKA, Y. KAGAWA, T. HONGO, T. HORIUCHI, N. ...
1985 Volume 14 Issue 3 Pages
1223-1226
Published: June 15, 1985
Released on J-STAGE: October 07, 2011
JOURNAL
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The in vivo and in vitro sensitivity and stability of intravascular ISFET sensors (pH, pCO
2) and piezoresistive pressure sensors for an artificial heart device have been investigated.
After a logarithmic initial drift for an hour, pH sensors showed an average longterm drift of 0.01 pH h
-1. The micro sensors responded rapidly enough to applyy for an automaticc control system of the artificial heart.
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