Abstract
The enzymes, cathechoramine and metabolic changes were studied by three dimensional graph in one hundred twenty six patients with extracorporeal circulation with core cooling . The following results were obtained 1) The lactic acid metabolism and carbohydrate metabolism were correlated to perfusion period rather than low body temparature by core cooling. 2) The influence on changes of enzymes with extracorporeal circulation was indicated by CPK rather than LDH or GOT. 3) The low perfusion pressure at immediate periods on extracorporeal circulation was correlated to bloody kinin level rather than serum adrenal in levels.