Abstract
The effect of bio-pump and roller pump on hemolysis was compared by measuring free Hb concentration in the circulatory blood. In the experiments, bovine blood was circulated in the closed circuit by using each of the pumps. After 2 hour circulation, free Hb concentration was lower in the group of using bio-pump than that of roller pump. During 24 hour free Hb concentration was gradually increased in both groups, and after 24 hour circulation, there was no significant defference of free Hb concentration between the groups. The bio-pump was used in five patients undergoing open heart surgery. On the clinical use, there was no significant difference of free Hb concentration between the group of using bio-pump and roller pump. However, bio-pump was considered one of the efficient pumps applicable to the clinical use.