Jinko Zoki
Online ISSN : 1883-6097
Print ISSN : 0300-0818
ISSN-L : 0300-0818
EFFECT OF METHYLPREDNISOLONE ON COMPLEMENT ACTIVATION DURING CARDIOPULMONARY BYPASS
Y. MIYAMOTO, H. HIROSE, H. MATSUDA, S. NAKANO, R. SHIRAKURA, S. NAKATA, M. OHTANI, K. KADOBA, N. OHKUBO, S. KUKI, F. NOMURA, Y. KAWASHIMA
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Keywords: complement activation, cardiopulmonary bypass, methylprednisolone, alternative pathway, anaphylatoxin
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1986 Volume 15 Issue 2 Pages 968-971

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Abstract
In vitro experiment, methylprednisolone inhibited complement activation via both pathways, especially alternative pathway. In clinical cardiopulmonary bypass, methylprednisolone significantly inhibited complement activation via alternative pathway.
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