Experimental induced chronic heart failure

Abstract

To induce the chronic heart failure in 8 dogs, we implanted 5-7 electrodes in multiple branches of the left coronary artery and partially ligated the main left anterior descending coronary artery immediately distal to the first septal artery. The electrodes were activated sequentially semiweekly by application of 800μA, anodal current to each electrode. Comparison of parameters, measured by Swan-Ganz and Millar catheter before and after current application indicated significant left ventricular impairment in all dogs.