On the release of soluble components from dialyzer modules

Abstract

Since release of soluble components from dialyzer could be inocorporated into blood circulation, an extracts of rinsing fluid were analysed.After rinsing various module with 500ml distilled water, other 300ml of distilled water was circulated for 4hrs andanalysed. During the extracttion of soluble components, silicon was used at connecting portion of the module and also rolling part of blood pump, while teflon was used in the all other portions of the tubing. Transparency of the rinsing fluid was 98.7-100%. ΔpH between extract and blank was 0.48-1.47. Consumption of KMnO4 was 1.1-19.3ml. Infrared absorption of the extract revealed the same pattern as membrane materials in the modules sterilized with r-ray. Glycerin peak was noticed in the dry typemodules. Without adequate rinsing of the dialyzer, there is a possibility of incorpiration of soluble components into the blood. It is recommended to rinse the dialyzer modules well enough to wash out those components before use.