1987 Volume 16 Issue 2 Pages 791-794
The removal of plasma proteins (β2-microglobulin, retinol binding protein and albumin) was studied with sane high-performance filter at proteinpermeating hemodiafiltration. The sieving coefficients (SC) of β2-microglobulin were: KF101-15C, 0.55; TAF102S, 0.40; Duo-Flux, 0.32; H12-2400S, 0.29; AM-2400UP, 0.42; TF-E15P, 0.33. The SC of albumin were: KF101-15C, 0.08; TAF 120S, 0.02; Duo-Flux HP, H12-2400S, AM-2000UP and TF-E15P, below 0.01. The removing ratio of β2-microglobulin to albumin were: KF101-15C, 1.3%; TAFI20S, 4.7%; Duo-Flux HP, 9.1%; AM-2000UP, 7.1%; TF-E15P, 7.2%; H12-2400S, 312%. A high removing ratio of β2-microglobulin to albumin was observed in use of H12-2400S (PAN) membrane, eapared with EVAL and cellulose membrane. It will be possible to select a high-performance filter suitable for each patient.
