1987 Volume 16 Issue 2 Pages 800-803
A Limulus test-positive substance is eluted from the cellulose membrane dialyzer, and the serum of hemodialysis (HD) patients on this dialyzer is Limulus test positive. When the dialyzer wash solution (DWS) from the cuprophan membrane was added to peripheral blood roonocytes, interleukin-1 (IL-1) productivity significantly increased. However, DWS from the polymethylmetacrylate (PMMA) membrane was Limulus test negative and did not increase IL-1 productivity. Furthermore, IL-1 productivity of peripheral blood roonocytes from HD patients on the cuprophan membrane dialyzer was significantly higher than that for healthy controls and HD patients on the PMMA membrane dialyzer.
