1987 Volume 16 Issue 2 Pages 856-859
Extravascular lung water (EVLW) was examined in seven hemodialysis (HD) patients by means of double indicator dilution method, using Lung Water Computer (American Edwards Comp.). Concurrently, hemodynamics were measured by Swan-Ganz catheter, and arterial blood gases were analyzed, too. EVLW was the value 10.5±2.9ml/kg just before HD, it just increased up to 11.5ml/kg after the initiation of HD. Then, it decreased gradually with the times and finally took the value 10.3ml/kg at the end of HD. Both arterial oxygen tension and cardiac output decreased, on the other hand, pulmonary vascular resistance increased during HD. Judging from the increase in EVLW in spite of the removal of the body fluid during HD, the increase in EVLW attribute the elevation of pulmonary capillary permiability from unknown mechanism. So-called HD-induced hypoxemia may be related to the increase in EVLW. It is interesting that the increase in EVLW during HD may be related to hypersensitivity syndrome.