Abstract
It is well known that mist patients show impaired glucose tolerance after major operation. This tendency is often aggravated especially when these patients have severe infection. For such condition, sufficient nutritional support cannot be performed usually. We used artificial pancreas for nine postoperative patients with panperitonitis and studied the values of this device. [RESULTS] Glucose uptake was sufficient in most of the patients, in comparison with the resting energy expenditure with the use of this device. Blood sugar was able to be maintained between 140-220mg/dl usually. Therefore mean glucose uptake ratio was high up to 97.1% during this therapy. Much amount of insulin as much as 250mU/kg/hr was necessary, for a few patients. The ratio of given insulin per glucose uptake, which was suspected to reflect the change of glucose tolerance exactly, showed elevated values, initially. This tendency, however, seemed to have improved gradually, due to the improvement of this impaired glucose tolerance. [CONCLUSION] This device was thought to be useful for evaluating and also for treatment of the surgical diabetics.